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Demerol is a drug that’s used to treat pain. It’s also called meperidine or pethidine.
Demerol was first approved by the U.S. Food and Drug Administration (FDA) in 1960 and has been on sale since then as a single-dose product for use as an analgesic (pain reliever). The drug is available in several forms, including tablets and capsules; liquids in bottles with droppers; liquid suspension for injection; liquid suspension for oral administration; oral drops (liquid form); rectal suppositories coated with a binder containing esters of myristic acid/palmitic acid which are soluble in water but not alcohols or fatty oils
Mechanism of Action
The mechanism of action of morphine is to cause a release of endorphins in the brain. Endorphins are chemicals that provide pain-relieving and euphoric effects, making you feel good.
Morphine also works by blocking certain receptors on cells in your brain, which causes them to stop firing after they’ve fired once too often (known as hyperalgesia). This makes you feel less pain even though it’s still there, but it can also make you tired because your body doesn’t want to keep sending the same message over and over again—it wants something new!
- For the relief of moderate to moderately severe pain:
- Management of postoperative pain
- Control of pain in patients with terminal cancer who have failed to respond satisfactorily to other analgesics.
Dosage and Administration
- The recommended dosage of Demerol is 2 mg per pound of body weight every four hours.
- The duration of treatment with Demerol is usually 24 hours, but you may be given more than one dose if necessary.
Warnings and Precautions
- Warnings and Precautions
- Do not use this medicine if you are allergic to meperidine or other narcotic analgesics.
- Do not use this medicine in children younger than 8 years old without the advice of your doctor. The safety and effectiveness of Diclofenac Injection for children under 18 years have not been established.
- Call your doctor at once if you have any signs of an allergic reaction to Diclofenac Injection (such as rash, hives; swelling of face, lips, tongue, or throat). This is a serious side effect that can lead to death
- Nausea and vomiting
- Dizziness and/or lightheadedness
- Drowsiness or fatigue, weakness, or confusion (particularly in older adults)
- Constipation or diarrhea
In the event of an overdose, call 911. You should also seek medical treatment immediately to prevent further damage to your body. If you suspect someone has overdosed on painkillers, call their doctor or go to their house and ask them whether they’re OK.
If possible, have someone else drive you to the ER while he waits in the car; this will prevent him from getting into an accident if he passes out while driving. If this isn’t possible and there’s no one near enough to help him get there (for example if he lives far away), try calling 9-1-1 for help instead!
The dosing of Demerol is dependent upon the severity of the pain, but most people take one tablet every 4 hours as needed. However, this dose may be increased to two tablets per day if needed. This medication should not be used in combination with other drugs without consulting your doctor first.